久保 いづみ(教授)

クボ イヅミ

専門分野 マイクロ・ナノデバイス
担当科目 分析化学、電気化学、機器分析学、生物電気化学、バイオエレクトロニクス、理工学総論、演習Ⅰ・Ⅱ
研究テーマ 診断用バイオチップの開発

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工学研究科 生命情報工学専攻

  • 専門分野 分析化学、機器分析学、生物電気化学、バイオエレクトロニクス
    担当科目 分析化学、機器分析バイオエレクトロニクスなど
    研究テーマ 環境モニタリング用バイオセンサーの研究開発
    診断用バイオチップの研究開発
    主な著書論文 (1) 「バイオエレクトロニクス」(共著)朝倉書店
    ("Bioelectronics" joint work , Asakura shoten in Japanese)
    (2) "Bioinstrumentation Research, Developments and Applications" (共著)Butterworths Publishers
    (3) 「微生物センサーによる環境物質の計測」 化学工業 44, 816-821 (1993)
    ("Determination of environmental substances with microbial sensors" Kagakukogyo, 44, 816-821 (1993) in Japanese)
    (4) "Phosphate sensing system using pyruvate oxidase and chemiluminescence detection" (共著)
    Biosensors & Bioelectronics 11 , 959-965 (1996)
    (5)"Reagentless phosphate ion sensor system for envieonmental monitoring" Electrochemistry 66, 579-583 (1998)
    (6)"Sulfate binding protein modified electrode as a chemical sensor" IEICE Trans. Electron , E83-C , 1035-1039 (2000)
    (7)"Electrochemical oligonycleotide detection based on probe DNA modified gold electrode using cobalt phenanthroline complex" Trans IEE of JAPAN, 121-E, 559-563 (2001)
    (8)"Phosphatidylcholine monolayers observed with Brewster Angle Microscopy and p-A isotherms" Thin Solic Films 393, 80-85 (2001)
    (9)食品設備・機器辞典 保坂秀明 編「バイオセンサー」pp877-879, 産業調査会(2002)
    (10)バイオセンサー 軽部征夫 監修,「酵素センサー」pp21-32 シーエムシー出版 (2002)
    (11)Izumi Kubo“Potentionmetric phosphate-sensing system”Analytical and Bioanalytical Chemistry, 327, 273- 275(2002)
    (12)Shinya Watanabe and Izumi Kubo“Fructose Biosensor based on D-Fructose Dehydrogenase and Phenanthroline cobalt Complex as aMediator”,Electrochemistry, 70, 258-263 (2002)
    (13)久保いづみ,元家健太郎“in vivo測定用複合型マイクロイオンセンサ“Technical Report of
    IEICE, OME-2002-57, 13-18 (2002)
    (14)小路麗生,竹内俊文,鈴木博章,久保いづみ“モレキュラーインプリントポリマーを用いたアンペロメトリックアトラジンチップの研究”Chemical Sensors, 18 SupB, 7-9 (2002)
    (15)R. Shoji, T. Takeuchi and I. Kubo“Atrazine Sensor Based on Molecularly Imprinted Polymer-Modified Gold electrode”, Anal. Chem. 75, 4882-4886 (2003)
    (16)小路麗生,竹内俊文,鈴木博章,久保いづみ“ナノケミカルレセプター修飾電極を用いるアトラジンセンサーの開発” BUNSEKI KAGAKU,52, 1141-1146 (2003)
    (17)久保いづみ,前原信義“アスコルビン酸応答を除去した修飾電極とそのバイオセンサへの応用”,Chemical Sensors, 19 B, 70-72 (2003)
    (18)中根優子,久保いづみ“細胞膜モデルコンプレックス固定化QCMの環境ホルモンセンサへの応用”, Chemical Sensors, 19 B, 100−102 (2003)
    (19)Y. Moroi, M. Rusdi and I. Kubo,“Difference in Surface Properties between Insoluble Monolayer and Absorbed Film from Kinetics of Water Evaporation and BAM Image”, J. Phys. Chem. B, 108(20), 6351-6358 (2004)
    (20)Izumi Kubo and Daisuke Satoh“Preparation of Phosphate-Binding-Protein Modified electrode and Its Application to Reagentless Phosphate Sensor” Sensors and Materials,16(8) , 391-399 (2004)
    (21)R. Shoji, A. Shimizu, H. Suzuki and I. Kubo“CAT Imprinted polymer and Its Application to the Electrochemical Determination of CAT”The 10th International Meeting on Chemical Sensors,Chemical Sensors, 20 Suppl. B, 552-553 (2004)
    (22)Y. Nakane and I. Kubo“A novel sensing system for endocrine disrupting chemicals (EDCs) based on their hydrophobic interaction with model cell membranes”The 10th International Meeting on Chemical Sensors,Chemical Sensors, 20 Suppl. B, 616-617 (2004)
    (23)“Selective Measurement of Dopamine with an Alkanethiol-Modified Electrode”,I. Kubo, K. Yoshimura, N. Maehara, Chemical Sensors, 21 Suppl. A, 187-189 (2005)
    (24)“Study of the Preparation of Molecularly Imprinted Polymer Receptor for Simazine” Y. Fuchiwaki, A. Shimizu and I. Kubo, Chemical Sensors, 21 Suppl. A, 190-182 (2005)
    (25)”Selective Oxidation of Dopamine and Serotonine with an Alkanethiol-Modified Electrode, I. Kubo, K. Yoshimura and E. Ohashi, Electrochemistry, 74(2), 149-152 (2006)
    (26)"A carboxyalkanethiol monolayer modified electrode for blocking of ascorbic acid oxidation and its application to a biosensor", I. Kubo, Y. Nakane, N. Maehara, Electrochmica Acta, 51, 5163-5168 (2006)
    (27)ナノテクノロジーとバイオセンサ―酵素センサの原理と応用― 「臨床検査」,久保いづみ, 50(12),1449-1458(2006)
    (28) "6-Chloro-N,N-diethyl-1,3,5-triazine-2,4-diamine(CAT) Sensor Based on Biomimetic Recognition Utilizing a Molecularly Imprinted Artificial receptor", Y. Fuchiwaki, A. Shimizu, I. Kubo, Anal. Sci., (23), 49-53(2007)
    (29)"Development of electrochemical Sensing System for 6-Chloro-N,N-Diethyl-1,3,5-Triazine (CAT) Utilizing an Amalgamated Gold electrodeand Artificial Sensor Receptor", Y. Fuchiwaki, N. Sasaki and I. Kubo, Electrochemistry, 75(9), 709-714 (2007)
    (30)S. FURUTANI, H. NAGAI and I. KUBO*.
    Single cell isolation on a centrifugal flow disk with integrated tandem microchambers.
    Sensor Letters, Vol.6, No.6: pp.961-965, 2008.
    (31)N. MATSUNAGA, S. FURUTANI and I. KUBO*.
    Centrifugal Flow Device for High-throughput Detection of Cancer Marker CEA.
    ECS transactions: Chemical Sensors 8: Chemical (Gas, Ion, Bio) Sensors and Analytical Systems, Vol.16, No.11: pp.123-128, 2008.
    (32)N. YOKOTA, Y. FUCHIWAKI and I. KUBO*.
      Fabrication of bisphenol A sensor utilizing electrode modified with molecularly imprinted polymer.
      ECS Transactions. Vol.16, No.11: pp.551-556, 2008.
    (33)Y. Nakane and I. Kubo*
    Biosensor for the Detection of Endocrine Disrupting Chemicals Based on the Degradation of Cell Membrane Model Immobilized on QCM and Its Application to the Detection of Nonylphenol
    Electrochemistry, Vol.76, pp.535-537 , 2008
    (34)Y. Nakane , M. M. Ito and I. Kubo*
    Novel detection method of endocrine disrupting chemicals utilizing liposomes as cell membrane model
    Analytical Letters, Vol.41, pp.2923-2932, 2008
    (35)I. Kubo,* R. Shoji, Y. Fuchiwaki and H. Suzuki,
    Atrazine Sensing Chip Based on Molecularly Imprinted Polymer Layer,
    Electrochemistry, Vol.76, pp.541-544 , 2008
    (36)Y. Nakane and I. Kubo*
    Degradation of liposome cluster caused by the interaction with endocrine disrupting chemicals,
    Colloids and Surfaces B: Biointerfaces, Vol.66, pp.60-64 , 2008
    (37)Y. Fuchiwaki, R. Shoji, I. Kubo* and H. Suzuki,
    6-Chloro-N,N-Diethyl-1,3,5-Triazine-2,4-Diamine(Simazine) Electrochemical Sensing Chip Based on Biomimetic Recognition Utilizing a Molecularly Imprinted Polymer Layer on a Gold Chip,
    Analytical Letters, Vol.41, pp.1398-1407 , 2008
    (38)I. KUBO*, S. FURUTANI and H. NAGAI.
    The Activity Determination of Single Cell by Isolation and Cultivation on a Centrifugal Flow Disk.
    ECS transactions: Challenges to Single-Cell Engineering and Imaging Technology, in press.
    所属学会 日本化学会、電気化学会、American Chemical Society、生物工学会,分析化学会
    諸活動 電気化学会関東支部幹事(1992-1994)
    科学技術庁 技術予測委員会ライフサイエンス分科会委員(1996-1997)
    有機エレクトロニクス研究会専門委員(1996-2002)
    電気化学会理事 (1999-2002)
    International Meeting on Chemical Sensors 2004 実行委員 (2003-2004)
    Analytical Sciences, Associate Editor(2007-2009)
    Sensors and Materials, Guest Editor(2015)

ページ公開日:2017年08月07日
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